Indications and procedures for direct immunofluorescence biopsies of the oral mucosa.

نویسندگان

  • Jose Luis Tapia
  • Mirdza E Neiders
  • Lakshmanan Suresh
چکیده

A definitive diagnosis is crucial for management of any oral mucosal disease. Direct immunofluorescence (DIF) is a valuable diagnostic aid for immune-mediated blistering diseases and systemic connective tissue diseases of the skin and the mucosa. This paper gives an overview of the DIF biopsy technique for oral lesions and provides a background for the clinician to optimize the utilization of DIF biopsy. The key characteristic diagnostic findings of DIF of specific mucosal diseases are also discussed.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Laryngeal manifestations in atypical recurrent aphthous stomatitis.

UNLABELLED Recurrent aphthoid stomatitis is characteristically observed in children and adolescents in the form of painful relapsing ulcers in the oral mucosa unaccompanied by evidences of systemic disease. The ulcers appear every one or two weeks for at least one entire year. Some patients suspected for recurrent aphthoid stomatitis develop lesions in atypical sites - mainly in the larynx - co...

متن کامل

بررسی اپیدمیولوژی لیکن پلان و آزمایش ایمونوفلورسانس مستقیم بر روی مقاطع پارافینه آن

Frequently, diagnosis of lichen planus as a relative common chronic inflammatory mucocutaneous disease, is difficult, therefor, direct Immunofluorescence (DIF) examination is recommended for definite diagnosis. In this study both an statistical analysis of files of oral and maxillofacial pathology department of Dentistry school and direct immunofluorescence examination using paraffin blocks wit...

متن کامل

بررسی ایمونوهیستوشیمیایی رسپتورهای استروژن و پروژسترون در ضایعات ژآنت سل گرانولومای محیطی و مرکزی فکین

Background and Aim: Giant cell granuloma is a relatively common benign proliferative lesion of the oral cavity. This lesion has a marked gender predilection with more prevalence in females and tendency to rapid growth and recurrence during pregnancy. The aim of this study was the evaluation of specific receptors of sex hormones in giant cell granuloma. Materials and Methods: In this cross-secti...

متن کامل

Diagnostic value of direct immunofluorescence of mucosal and skin biopsy specimens on formalin-fixed paraffin-embedded biopsy specimens compared to specimens placed in normal saline as the gold standard method in the diagnosis of a group of autoimmun

Background and Aim: Direct immunofluorescence (DIF) is represented as a gold standard method in diagnosis of autoimmune blistering dermatoses. Normal saline, liquid nitrogen and michel’ solution are a widely accepted media for preserving biopsy samples of skin or mucosa before DIF examination. Occasionally clinicians put the biopsy specimen taken for DIF in formalin 10%, occasionally clinicians...

متن کامل

Chronic ulcerative stomatitis: clinical, histopathologic, and immunopathologic findings.

Chronic ulcerative stomatitis (CUS) is a mucocutaneous disease primarily involving mucosal surfaces, but occasionally may involve the skin. Clinically, CUS patients exhibit erosive or ulcerative lesions of the oral mucosa that resemble erosive oral lichen planus. Direct immunofluorescence (DIF) studies of mucosal or skin biopsies reveal a unique pattern of IgG immunoglobulin bound to nuclei of ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Quintessence international

دوره 46 3  شماره 

صفحات  -

تاریخ انتشار 2015